Just after 4 p.m. today a Prius turned onto Mission Street at 23rd Street as a Muni bus heading north was crossing through a green light. The Prius hitting the bus, a pedestrian and two bus passengers.

Two of the victims, a 49-year-old male San Francisco resident and a 34-year-old male San Francisco resident, are in critical condition.

The third victim, a woman, was grazed in the collision.  The female bus passenger was evaluated for a complaint of pain and released at the scene.

In the aftermath, police closed down parts of Mission Street around 4:45 p.m. between 22nd and 23rd streets. At 6:16 p.m. police closed Mission Street to 24th Street.

Some bystanders said the Prius was moving fast. Police said the driver was being tested for alcohol and drugs.

Wendy Flores and her daughter Daniela said they saw a man in a purple car run over one pedestrian.

Police said the incidents began sometime after 4 p.m. when a burgundy-colored Toyota Prius traveling westbound on 23rd Street turned north onto Mission Street.

The driver accelerated and, according to police, made contact with the Muni bus and then struck a pedestrian in the crosswalk before jumping onto the curb and hitting one bus passenger “badly,” police said. The vehicle grazed a third person, a female bus passenger.

The driver of the Prius and his passenger initially fled the scene in the vehicle, but returned five minutes later, according to police.

His female passenger was not detained.

Muni buses have been diverted off of Mission Street.

An injured pedestrian from the bus stopped at 23rd and Mission. Photo by Loi Almeron.

The driver of the Prius is the man walking toward the woman, according to police. Photo by Loi Almeron.

The bus stop where the second pedestrian was hit. Photo by Loi Almeron.

The scene on Mission Street after 4 p.m Photo by Loi Almeron.

Mission Street after Wednesday’s collision. Photo by Loi Almeron.

Photo by Loi Almeron.